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LeadR Profile


Luigi Ferrucci
National Institute on Aging
United States

SLR Geriatrics ScienceLeadR Reputation 100%

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Health Specialties

Main specialty  Geriatrics
Full career - Last 3 years

Main Topics

Publications and Clinical Trials


Publications - Clinical Trials

Education

Academic Background

Source: ORCID

Organization

all information about organizations

Source: Pubmed

National Institute on Aging

National Institutes of Health

Institute of Clinical and Experimental Lymphology

MedStar Harbor Hospital

Pennington Biomedical Research Center

Istituto Superiore di Sanità

Charité - University Medicine Berlin

Istituto Nazionale di Riposo e Cura per Anziani

Awards and Honors

Source: ORCID

Academic Societies

Source: ORCID

Publications Synthesis

Source: Pubmed

Number : 1785

Citations

Citations: 101 401 1st author: 55 Last author: 447 Unique author: 4

Main journals

J Gerontol A Biol Sci Med Sci 214
J Am Geriatr Soc 129
Aging Cell 40
Nat Genet 36
Aging Clin Exp Res 33

Best Journals

JAMA 17
Nature 13
N Engl J Med 3

Breakdown by type

Historic per year



Main pathologies and trends

Publications List

Quick search selection

Source: Pubmed Source: OpenAlex
Title Journal CIT SLR Year
Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts. BMJ
36653033
2 105.7 2023
Biomarkers of aging for the identification and evaluation of longevity interventions. Cell
37657418
16 64.5 2023
The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis. Lancet Diabetes Endocrinol
37696273
2 44.5 2023
Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies. Circulation
38047387
1 37.8 2023
Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease: JACC Scientific Statement. J Am Coll Cardiol
37389519
2 24 2023
Mitophagy in human health, ageing and disease. Nat Metab
38036770
1 20.8 2023
Transcriptomic and Proteomic of Gastrocnemius Muscle in Peripheral Artery Disease. Circ Res
37154037
5 20.1 2023
Obesity and lifespan, a complex tango. Sci Transl Med
37992154
0 17.1 2023
SARS-CoV-2 infection establishes a stable and age-independent CD8 T cell response against a dominant nucleocapsid epitope using restricted T cell receptors. Nat Commun
37872153
0 16.6 2023
Genetic insights into resting heart rate and its role in cardiovascular disease. Nat Commun
37532724
0 16.6 2023
Challenges in developing Geroscience trials. Nat Commun
37598227
3 16.6 2023
Virus exposure and neurodegenerative disease risk across national biobanks. Neuron
36669485
34 16.2 2023
DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice. J Clin Invest
37097759
2 15.9 2023
Large-scale rare variant burden testing in Parkinson's disease. Brain
37348876
3 14.5 2023
Skeletal muscle mitochondrial function predicts cognitive impairment and is associated with biomarkers of Alzheimer's disease and neurodegeneration. Alzheimers Dement
37530130
4 14 2023
Longitudinal changes in Alzheimer's-related plasma biomarkers and brain amyloid. Alzheimers Dement
37216632
4 14 2023
Association of common infections with cognitive performance in the Baltimore Epidemiologic Catchment Area study follow-up. Alzheimers Dement
37027458
2 14 2023
Lower myelin content is associated with more rapid cognitive decline among cognitively unimpaired individuals. Alzheimers Dement
36720000
4 14 2023
Dual cognitive and mobility impairments and future dementia - Setting a research agenda. Alzheimers Dement
36637077
2 14 2023
Home-Based Walking Exercise and Supervised Treadmill Exercise in Patients With Peripheral Artery Disease: An Individual Participant Data Meta-Analysis. JAMA Netw Open
37733346
0 13.8 2023
Associations of olfactory function with brain structural and functional outcomes. A systematic review. Ageing Res Rev
37913831
0 13.1 2023
Health Conditions Associated with Alzheimer's Disease and Vascular Dementia. Ann Neurol
36571386
0 11.2 2023
Genome-Wide Analysis of Structural Variants in Parkinson Disease. Ann Neurol
36695634
8 11.2 2023
Proteomic Indicators of Health Predict Alzheimer's Disease Biomarker Levels and Dementia Risk. Ann Neurol
37801487
0 11.2 2023
Metabolomic markers mediate erythrocyte anisocytosis in older adults: Results from three independent aging cohorts. J Intern Med
36739565
0 11.1 2023
Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease. Mol Psychiatry
37198259
7 11 2023
Correction to: Plasma proteins related to inflammatory diet predict future cognitive impairment. Mol Psychiatry
36849825
0 11 2023
Plasma proteins related to inflammatory diet predict future cognitive impairment. Mol Psychiatry
36737481
3 11 2023
Correction: Midlife adiposity predicts earlier onset of Alzheimer's dementia, neuropathology and presymptomatic cerebral amyloid accumulation. Mol Psychiatry
37563279
1 11 2023
Hypertensive Adults Exhibit Lower Myelin Content: A Multicomponent Relaxometry and Diffusion Magnetic Resonance Imaging Study. Hypertension
37283066
2 8.3 2023
Identification of Clinically Relevant Brain Endothelial Cell Biomarkers in Plasma. Stroke
37814955
1 8.3 2023
Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH. Diabetologia
37233759
0 8.2 2023
Temporal trends, sex differences, and age-related disease influence in Neutrophil, Lymphocyte count and Neutrophil to Lymphocyte-ratio: results from InCHIANTI follow-up study. Immun Ageing
37667259
3 7.9 2023
Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways. Aging Cell
37309088
0 7.8 2023
Explainable machine learning framework to predict personalized physiological aging. Aging Cell
37300327
1 7.8 2023
Age-related changes in human skeletal muscle microstructure and architecture assessed by diffusion-tensor magnetic resonance imaging and their association with muscle strength. Aging Cell
37162031
1 7.8 2023
Cross-sectional analysis of healthy individuals across decades: Aging signatures across multiple physiological compartments. Aging Cell
37350292
2 7.8 2023
Enabling translational geroscience by broadening the scope of geriatric care. Aging Cell
38038340
2 7.8 2023
Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE study. Aging Cell
37823711
2 7.8 2023
Transcriptomes of human primary skin fibroblasts of healthy individuals reveal age-associated mRNAs and long noncoding RNAs. Aging Cell
37462262
1 7.8 2023
Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest. Elife
37083495
1 7.7 2023
Epigenetic signature of human immune aging in the GESTALT study. Elife
37589453
0 7.7 2023
The gut microbiome and regional fat distribution: Findings from the Baltimore Longitudinal Study of Aging. Obesity (Silver Spring)
37016727
1 6.9 2023
Apolipoprotein E gene variants shape the association between dietary fibre intake and cognitive decline risk in community-dwelling older adults. Age Ageing
36729469
0 6.7 2023
Skin Barrier Function and Cognition among Older Adults. J Invest Dermatol
36641132
1 6.5 2023
Impact of balance on the energetic cost of walking and gait speed. J Am Geriatr Soc
37528742
0 6.3 2023
EHRA expert consensus document on the management of arrhythmias in frailty syndrome, endorsed by the Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Latin America Heart Rhythm Society (LAHRS), and Cardiac Arrhythmia Society of Southern Africa (CASSA). Europace
37061780
10 6.1 2023
Macrophage Involvement in Aging-Associated Skeletal Muscle Regeneration. Cells
37174614
3 6 2023
Proteomic Mediators of Overall Cardiovascular Health on All-Cause Mortality. Nutrients
36771486
0 5.9 2023
Associations of baseline and longitudinal change in cerebellum volume with age-related changes in verbal learning and memory. Neuroimage
36958620
0 5.7 2023
Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses. Exerc Sport Sci Rev
37057904
2 5.7 2023
Longitudinal associations between use of antihypertensive, antidiabetic, and lipid-lowering medications and biological aging. Geroscience
37032369
1 5.6 2023
Plasma metabolomic signatures of dual decline in memory and gait in older adults. Geroscience
37052768
3 5.6 2023
Muscle quality, physical performance, and comorbidity are predicted by circulating procollagen type III N-terminal peptide (P3NP): the InCHIANTI follow-up study. Geroscience
37532926
1 5.6 2023
OVCH1 Antisense RNA 1 is differentially expressed between non-frail and frail old adults. Geroscience
37817005
0 5.6 2023
Correction to: Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno‑/GrimAge and DNA‑methylation based PAI1. Geroscience
37921956
0 5.6 2023
Sarcopenia: no consensus, no diagnostic criteria, and no approved indication-How did we get here? Geroscience
37996722
3 5.6 2023
Comparison of sleep parameters from wrist-worn ActiGraph and Actiwatch devices. Sleep
37257489
0 5.6 2023
Mitochondrial Complex Abundance, Mitophagy Proteins, and Physical Performance in People With and Without Peripheral Artery Disease. J Am Heart Assoc
36892048
1 5.4 2023
Aging and Inflammation. Cold Spring Harb Perspect Med
38052484
0 5.4 2023
Beyond the relationship between mitochondria and mobility in aging. Aging (Albany NY)
37315298
0 5.2 2023
DNAmFitAge: biological age indicator incorporating physical fitness. Aging (Albany NY)
36812475
9 5.2 2023
Editorial: Molecular crosstalk between endocrine factors, paracrine signals, and the immune system during aging. Front Endocrinol (Lausanne)
37152922
0 5.2 2023
Nutrient Metabolites Associated With Low D3Cr Muscle Mass, Strength, and Physical Performance in Older Men. J Gerontol A Biol Sci Med Sci
37694554
1 5.1 2023
Physiological Dysregulation Proceeds and Predicts Health Outcomes Similarly in Chinese and Western Populations. J Gerontol A Biol Sci Med Sci
37313838
1 5.1 2023
Geroscience for the Next Chapter of Medicine. J Gerontol A Biol Sci Med Sci
36915943
2 5.1 2023
The Effect of the Human Brainstem Myelination on Gait Speed in Normative Aging. J Gerontol A Biol Sci Med Sci
37555749
1 5.1 2023
Proteomic Analysis of the Senescence-Associated Secretory Phenotype: GDF-15, IGFBP-2, and Cystatin-C Are Associated With Multiple Aging Traits. J Gerontol A Biol Sci Med Sci
37982669
1 5.1 2023
A Dietary Holy Grail for Healthy Aging? J Gerontol A Biol Sci Med Sci
36825619
0 5.1 2023
Shared and Distinct Associations of Manual Dexterity and Gross Motor Function With Brain Atrophy. J Gerontol A Biol Sci Med Sci
37837441
0 5.1 2023
Beyond Inflammaging: The Impact of Immune System Aging on Age-Related Muscle Decline, Results From the InCHIANTI Study. J Gerontol A Biol Sci Med Sci
37795971
0 5.1 2023
Relationships of GDF8 and 11 and Their Antagonists With Decline of Grip Strength Among Older Adults in the Baltimore Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci
37235639
0 5.1 2023
Novel Potential Targets for Function-Promoting Therapies: Orphan Nuclear Receptors, Anti-inflammatory Drugs, Troponin Activators, Mas Receptor Agonists, and Urolithin A. J Gerontol A Biol Sci Med Sci
37325960
1 5.1 2023
Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8, and Their Binding Proteins, Follistatin and Follistatin-Like Protein-3, With Measures of Skeletal Muscle Mass, Muscle Strength, and Physical Function in Older Adults. J Gerontol A Biol Sci Med Sci
36752218
2 5.1 2023
The association between personality and plasma biomarkers of astrogliosis and neuronal injury. Neurobiol Aging
37210782
6 4.2 2023
Upregulation of Sarcolemmal Hemichannels and Inflammatory Transcripts with Neuromuscular Junction Instability during Lower Limb Unloading in Humans. Biology (Basel)
36979123
0 4.2 2023
Sex differences in plasma lipid profiles of accelerated brain aging. Neurobiol Aging
37336172
1 4.2 2023
Human Metabolome Reference Database in a Biracial Cohort across the Adult Lifespan. Metabolites
37233632
1 4.1 2023
Perceived Fatigability, Fatigue, and Mortality in Mid-to-Late Life in the Baltimore Longitudinal Study of Aging. Med Sci Sports Exerc
37847074
0 4.1 2023
Frailty from conceptualization to action: the biopsychosocial model of frailty and resilience. Aging Clin Exp Res
36944846
0 4 2023
Age-related changes in gait biomechanics and their impact on the metabolic cost of walking: Report from a National Institute on Aging workshop. Exp Gerontol
36693530
4 3.9 2023
A multidimensional approach to older patients during COVID-19 pandemic: a position paper of the Special Interest Group on Comprehensive Geriatric Assessment of the European Geriatric Medicine Society (EuGMS). Eur Geriatr Med
36656486
1 3.8 2023
Hospitalizations during home-based walking exercise interventions in peripheral artery disease: Results from two randomized clinical trials. Vasc Med
37622748
0 3.5 2023
Blood Biomarkers for Healthy Aging. Gerontology
37166337
0 3.5 2023
Identification of glycolytic proteins as binding partners of Bri2 BRICHOS domain. J Pharm Biomed Anal
37220701
0 3.4 2023
Author Correction: Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial. Nat Aging
37161091
0 0.01 2023
Longitudinal Variability Analysis on Low-dose Abdominal CT with Deep Learning-based Segmentation. Proc SPIE Int Soc Opt Eng
37465093
0 0.01 2023
Leveraging longitudinal diffusion MRI data to quantify differences in white matter microstructural decline in normal and abnormal aging. bioRxiv
37292885
0 0 2023
Single slice thigh CT muscle group segmentation with domain adaptation and self-training. J Med Imaging (Bellingham)
37448597
0 0 2023
Study Design, Rationale, and Methodology for Promote Weight Loss in Patients With Peripheral Artery Disease Who Also Have Obesity: The PROVE Trial. J Am Heart Assoc
37642035
0 0 2023
Looking at frailty and intrinsic capacity through a geroscience lens: the ICFSR & Geroscience Task Force. Nat Aging
37985720
0 0 2023
Unbiased proteomics and multivariable regularized regression techniques identify SMOC1, NOG, APCS, and NTN1 in an Alzheimer's disease brain proteomic signature. NPJ Aging
37414805
3 0 2023
Multiomics integration of 22 immune-mediated monogenic diseases reveals an emergent axis of human immune health. Res Sq
36993430
0 0 2023
Effect of Neurotoxin Exposure on Blood Biomarkers of Neurodegeneration and Alzheimer Disease. Alzheimer Dis Assoc Disord
37698523
0 0 2023
Identification of circulating proteins associated with general cognitive function among middle-aged and older adults. Commun Biol
37923804
1 0 2023
Plant Protein but Not Animal Protein Consumption Is Associated with Frailty through Plasma Metabolites. Nutrients
37836476
0 0 2023
Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias. Cell Genom
37388914
4 0 2023
Longitudinal changes in Alzheimer's-related plasma biomarkers and brain amyloid. medRxiv
36711545
0 0 2023
Survey of organ-derived small extracellular vesicles and particles (sEVPs) to identify selective protein markers in mouse serum. J Extracell Biol
37744304
1 0 2023
Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial. Nat Aging
37118425
14 0 2023
Application and validation of an algorithmic classification of early impairment in cognitive performance. medRxiv
36798178
0 0 2023
Higher testosterone and testosterone/estradiol ratio in men are associated with better epigenetic estimators of mortality risk. medRxiv
36865294
0 0 2023
Temporal trends, sex differences, and age-related disease influence in Neutrophil, Lymphocyte count and Neutrophil to Lymphocyte-ratio. Results from InCHIANTI follow-up study. Res Sq
37461588
1 0 2023
Decoding Angiotensin Receptors: TOMAHAQ-Based Detection and Quantification of Angiotensin Type-1 and Type-2 Receptors. J Am Heart Assoc
37681524
0 0 2023
Sensory impairment and algorithmic classification of early cognitive impairment. Alzheimers Dement (Amst)
37063388
1 0 2023
Navigating and diagnosing cognitive frailty in research and clinical domains. Nat Aging
37845509
1 0 2023
Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering. ArXiv
36748000
0 0 2023
Sensory impairment and beta-amyloid deposition in the Baltimore longitudinal study of aging. Alzheimers Dement (Amst)
37139098
0 0 2023
Application and validation of an algorithmic classification of early impairment in cognitive performance. Aging Ment Health
37354067
1 0 2023
Leveraging longitudinal diffusion MRI data to quantify differences in white matter microstructural decline in normal and abnormal aging. Alzheimers Dement (Amst)
37780863
1 0 2023
Effect of Telmisartan on Walking Performance in Patients With Lower Extremity Peripheral Artery Disease: The TELEX Randomized Clinical Trial. JAMA
36194220
1 120.7 2022
A saturated map of common genetic variants associated with human height. Nature
36224396
81 64.8 2022
Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health
35247352
74 50 2022
DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity. Immunity
35704994
2 32.4 2022
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. Nat Genet
36071172
30 30.8 2022
Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited. JAMA Psychiatry
35921104
5 25.8 2022
Heterogeneity and transcriptome changes of human CD8 T cells across nine decades of life. Nat Commun
36050300
7 16.6 2022
Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets. J Clin Invest
35708913
12 15.9 2022
Connecting aging biology and inflammation in the omics era. J Clin Invest
35838044
29 15.9 2022
CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure. J Exp Med
35687056
5 15.3 2022
Proteins in the pathway from high red blood cell width distribution to all-cause mortality. EBioMedicine
35065420
5 11.1 2022
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood. Biol Psychiatry
36759259
3 10.6 2022
Utility of plasma cell-free DNA for detection and quantification of clonal hematopoiesis. Haematologica
34587721
2 10.1 2022
Genetic Variation in Targets of Antidiabetic Drugs and Alzheimer Disease Risk: A Mendelian Randomization Study. Neurology
35654594
5 9.9 2022
Associations of Olfaction With Longitudinal Trajectories of Brain Volumes and Neuropsychological Function in Older Adults. Neurology
36460474
4 9.9 2022
Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies. Am J Hum Genet
36055212
2 9.8 2022
Profiling the NOTCH2NLC GGC Repeat Expansion in Parkinson's Disease in the European Population. Mov Disord
35866887
1 8.6 2022
Higher Arm Versus Lower Arm Systolic Blood Pressure and Cardiovascular Outcomes: a Meta-Analysis of Individual Participant Data From the INTERPRESS-IPD Collaboration. Hypertension
35916147
1 8.3 2022
Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span. Aging Cell
35429111
7 7.8 2022
Integrative analysis of clinical and epigenetic biomarkers of mortality. Aging Cell
35546478
2 7.8 2022
Muscle mitochondrial energetics predicts mobility decline in well-functioning older adults: The baltimore longitudinal study of aging. Aging Cell
35048491
19 7.8 2022
Single-cell analysis of skeletal muscle macrophages reveals age-associated functional subpopulations. Elife
36259488
11 7.7 2022
Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians. Elife
35404238
6 7.7 2022
Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies. Elife
36537669
4 7.7 2022
Getting closer to the clinic. Elife
35212264
1 7.7 2022
Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis. Int J Epidemiol
35726641
11 7.7 2022
The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet is associated with physical function and grip strength in older men and women. Am J Clin Nutr
34637504
7 7.1 2022
Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration. Transl Psychiatry
35501309
4 6.8 2022
Comprehensive geriatric assessment in older people: an umbrella review of health outcomes. Age Ageing
35524746
13 6.7 2022
Association between walking energy utilisation and longitudinal cognitive performance in older adults. Age Ageing
36571773
1 6.7 2022
Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia. Int J Cancer
35579976
7 6.4 2022
Metabolomic Profile of Different Dietary Patterns and Their Association with Frailty Index in Community-Dwelling Older Men and Women. Nutrients
35684039
1 5.9 2022
Quality Specific Associations of Carbohydrate Consumption and Frailty Index. Nutrients
36501101
3 5.9 2022
Urinary and Daily Assumption of Polyphenols and Hip-Fracture Risk: Results from the InCHIANTI Study. Nutrients
36432441
1 5.9 2022
Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies. Eur J Endocrinol
36070417
5 5.8 2022
Differential associations between apolipoprotein E alleles and cerebral myelin content in normative aging. Neuroimage
35150834
3 5.7 2022
Angiotensin receptor blocker use is associated with upregulation of the memory-protective angiotensin type 4 receptor (ATR) in the postmortem brains of individuals without cognitive impairment. Geroscience
35969296
1 5.6 2022
A metabolomic signature of the APOE2 allele. Geroscience
35997888
2 5.6 2022
Longitudinal associations between blood lysophosphatidylcholines and skeletal muscle mitochondrial function. Geroscience
35389191
5 5.6 2022
Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop. Geroscience
36242692
3 5.6 2022
Biomarkers of aging in real life: three questions on aging and the comprehensive geriatric assessment. Geroscience
35796977
9 5.6 2022
Effects of short-term unloading and active recovery on human motor unit properties, neuromuscular junction transmission and transcriptomic profile. J Physiol
36071599
3 5.5 2022
Effects of Walking Exercise at a Pace With Versus Without Ischemic Leg Symptoms on Functional Performance Measures in People With Lower Extremity Peripheral Artery Disease: The LITE Randomized Clinical Trial. J Am Heart Assoc
35894088
1 5.4 2022
Dysregulated Genes, MicroRNAs, Biological Pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A Preliminary Analysis. J Am Heart Assoc
36300658
2 5.4 2022
DNA methylation GrimAge version 2. Aging (Albany NY)
36516495
16 5.2 2022
Hearing and Mobility in Aging-The Moderating Role of Neuropsychological Function. J Gerontol A Biol Sci Med Sci
35226729
1 5.1 2022
Plasma Growth and Differentiation Factor 15 Predict Longitudinal Changes in Bone Parameters in Women, but Not in Men. J Gerontol A Biol Sci Med Sci
35363860
1 5.1 2022
Associations Between Objectively Measured Sleep and Cognition: Main Effects and Interactions With Race in Adults Aged ≥50 Years. J Gerontol A Biol Sci Med Sci
36082967
2 5.1 2022
Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults. J Gerontol A Biol Sci Med Sci
35511890
2 5.1 2022
Longitudinal Associations of Subclinical Hearing Loss With Cognitive Decline. J Gerontol A Biol Sci Med Sci
34516645
8 5.1 2022
Motor and Physical Function Impairments as Contributors to Slow Gait Speed and Mobility Difficulty in Middle-Aged and Older Adults. J Gerontol A Biol Sci Med Sci
34984437
4 5.1 2022
Higher Angiotensin II Type 1 Receptor Levels and Activity in the Postmortem Brains of Older Persons with Alzheimer's Dementia. J Gerontol A Biol Sci Med Sci
34914835
8 5.1 2022
Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis. FASEB J
35073429
7 4.8 2022
Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies. Front Psychiatry
35273528
0 4.7 2022
Assessment of variability in the plasma 7k SomaScan proteomics assay. Sci Rep
36229504
19 4.6 2022
HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells. Sci Rep
35428779
2 4.6 2022
Longitudinal associations between energy utilization and brain volumes in cognitively normal middle aged and older adults. Sci Rep
35440799
1 4.6 2022
Acetyl-cholinesterase-inhibitors slow cognitive decline and decrease overall mortality in older patients with dementia. Sci Rep
35842477
5 4.6 2022
Aberrant expression and localization of the RAP1 shelterin protein contribute to age-related phenotypes. PLoS Genet
36441670
3 4.5 2022
Accelerated decline in white matter microstructure in subsequently impaired older adults and its relationship with cognitive decline. Brain Commun
35356033
7 4.37 2022
Causal links among amyloid, tau, and neurodegeneration. Brain Commun
35938073
5 4.37 2022
Associations of circadian rest/activity rhythms with cognition in middle-aged and older adults: Demographic and genetic interactions. Front Neurosci
36312032
1 4.3 2022
Longitudinal associations of absolute versus relative moderate-to-vigorous physical activity with brain microstructural decline in aging. Neurobiol Aging
35544996
3 4.2 2022
Associations of sensory and motor function with blood-based biomarkers of neurodegeneration and Alzheimer's disease in midlife. Neurobiol Aging
36209638
3 4.2 2022
The Plasma Proteome Fingerprint Associated with Circulating Carotenoids and Retinol in Older Adults. J Nutr
34550359
1 4.2 2022
Metabolites Associated with Memory and Gait: A Systematic Review. Metabolites
35448544
4 4.1 2022
Five-factor model personality traits and 24-h urinary cortisol in the Baltimore Longitudinal Study of Aging. Stress Health
35099848
0 4.1 2022
Predicting risk of declining functional ability in community-dwelling older people. Arch Gerontol Geriatr
36470178
1 4 2022
Olfaction, Cognitive Impairment, and PET Biomarkers in Community-Dwelling Older Adults. J Alzheimers Dis
35180111
9 4 2022
Daily Physical Activity Patterns as a Window on Cognitive Diagnosis in the Baltimore Longitudinal Study of Aging (BLSA). J Alzheimers Dis
35599480
2 4 2022
Prior psychosocial profile and perceived impact of the COVID-19 pandemic: insights from the Baltimore Longitudinal Study of Aging. Aging Clin Exp Res
35471695
0 4 2022
Multi-atlas segmentation and quantification of muscle, bone and subcutaneous adipose tissue in the lower leg using peripheral quantitative computed tomography. Front Physiol
36311235
1 3.892 2022
Identification of gingerenone A as a novel senolytic compound. PLoS One
35349590
2 3.7 2022
Cigarette smoking and mitochondrial dysfunction in peripheral artery disease. Vasc Med
36567551
0 3.5 2022
Multidimensional frailty and quality of life: data from the English Longitudinal Study of Ageing. Qual Life Res
35579730
4 3.5 2022
Associations of audiometric hearing and speech-in-noise performance with cognitive decline among older adults: The Baltimore Longitudinal Study of Aging (BLSA). Front Neurol
36570462
2 3.4 2022
Validation of accelerometer placement to capture energy expenditure using doubly labeled water. Appl Physiol Nutr Metab
35939837
0 3.4 2022
Trajectories of Frailty With Aging: Coordinated Analysis of Five Longitudinal Studies. Innov Aging
35233470
3 3.396 2022
An objective metric of individual health and aging for population surveys. Popul Health Metr
35361249
1 3.3 2022
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Anemia in older adults. Curr Opin Hematol
15725902
56 3.2 2005
Change in self-rated health and mortality among community-dwelling disabled older women. Gerontologist
15799986
18 2.772 2005
The hormonal pathway to frailty in older men. J Endocrinol Invest
16760619
24 2.633 2005
Acute changes in circulating hormones in older patients with impaired ventricular function undergoing on-pump coronary artery bypass grafting. J Endocrinol Invest
16277167
17 2.633 2005
The relationship between testosterone and molecular markers of inflammation in older men. J Endocrinol Invest
16760639
74 2.633 2005
Clinical implications of the reduced activity of the GH-IGF-I axis in older men. J Endocrinol Invest
16760634
33 2.633 2005
The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy. Aging Clin Exp Res
16485867
20 1.394 2005
Renal function, erythropoietin, and anemia of older persons: the InCHIANTI study. Arch Intern Med
16246987
30 0 2005
From bedside to bench: research agenda for frailty. Sci Aging Knowledge Environ
16079413
94 0 2005
Clinical and biochemical evaluation changes over aging. Cancer Treat Res
15839194
0 0 2005
Insulin resistance in cognitive impairment: the InCHIANTI study. Arch Neurol
16009759
37 0 2005
Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms. JAMA
15280343
238 44.405 2004
Relationship of alcohol intake with inflammatory markers and plasminogen activator inhibitor-1 in well-functioning older adults: the Health, Aging, and Body Composition study. Circulation
14769682
54 19.309 2004
Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood
15238427
396 13.164 2004
The origins of age-related proinflammatory state. Blood
15572589
386 13.164 2004
Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study. Am J Clin Nutr
14749236
122 6.926 2004
Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci
15031310
1199 5.957 2004
Effect of DHEAS on skeletal muscle over the life span: the InCHIANTI study. J Gerontol A Biol Sci Med Sci
15123757
43 5.957 2004
Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci
15031308
353 5.957 2004
Hemoglobin levels and skeletal muscle: results from the InCHIANTI study. J Gerontol A Biol Sci Med Sci
15031309
69 5.957 2004
Neurological examination findings to predict limitations in mobility and falls in older persons without a history of neurological disease. Am J Med
15178496
32 5.55 2004
Vitamin E levels, cognitive impairment and dementia in older persons: the InCHIANTI study. Neurobiol Aging
15748776
38 5.117 2004
Insulin resistance and executive dysfunction in older persons. J Am Geriatr Soc
15450050
31 4.388 2004
Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc
15086651
175 4.388 2004
Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report. J Am Geriatr Soc
15066083
310 4.388 2004
What constitutes normal hemoglobin concentration in community-dwelling disabled older women? J Am Geriatr Soc
15507056
48 4.388 2004
Diverse effect of inflammatory markers on insulin resistance and insulin-resistance syndrome in the elderly. J Am Geriatr Soc
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39 4.388 2004
Incidence of loss of ability to walk 400 meters in a functionally limited older population. J Am Geriatr Soc
15571549
38 4.388 2004
Inflammatory and thrombotic blood markers and walking-related disability in men and women with and without peripheral arterial disease. J Am Geriatr Soc
15507067
15 4.388 2004
Chlamydia pneumoniae seropositivity and cardiovascular risk factors: The InCHIANTI Study. J Am Geriatr Soc
15450037
4 4.388 2004
Impairments of muscles and nerves associated with peripheral arterial disease and their relationship with lower extremity functioning: the InCHIANTI Study. J Am Geriatr Soc
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55 4.388 2004
Bone density and hemoglobin levels in older persons: results from the InCHIANTI study. Osteoporos Int
15455197
36 3.591 2004
Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study. Exp Gerontol
15489066
58 3.34 2004
The role of soluble interleukin-6 receptor in inflammatory diseases. Immunol Lett
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Dietary intake estimated using different methods in two Italian older populations. Arch Gerontol Geriatr
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29 2.086 2004
Inflammatory markers, D-dimer, pro-thrombotic factors, and physical activity levels in patients with peripheral arterial disease. Vasc Med
15521700
9 1.866 2004
A flame burning within. Aging Clin Exp Res
15462468
28 1.394 2004
Informed consent for research participation in frail older persons. Aging Clin Exp Res
15132296
5 1.394 2004
Screening for poor performance of lower extremity in primary care: the Camucia Project. Aging Clin Exp Res
15575129
10 1.394 2004
The quality of bone: a "magic natural alloy". Aging Clin Exp Res
15506693
3 1.394 2004
Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians. Aging Clin Exp Res
15462469
25 1.394 2004
A pilot exercise intervention to improve lower extremity functioning in peripheral arterial disease unaccompanied by intermittent claudication. J Cardiopulm Rehabil
15235301
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Epidemiological profile of symptomatic osteoarthritis in older adults: a population based study in Dicomano, Italy. Ann Rheum Dis
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47 12.811 2003
Progression of lower-extremity disability in older women with diabetes: the Women's Health and Aging Study. Diabetes Care
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33 11.857 2003
Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study. Biol Psychiatry
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Risk factors for falling in home-dwelling older women with stroke: the Women's Health and Aging Study. Stroke
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68 6.032 2003
A comparison of leg power and leg strength within the InCHIANTI study: which influences mobility more? J Gerontol A Biol Sci Med Sci
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Anemia and decline in physical performance among older persons. Am J Med
12893395
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Inflammation, hormones, and body composition at a crossroad. Am J Med
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9 5.55 2003
Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women. J Clin Endocrinol Metab
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The frailty syndrome: a critical issue in geriatric oncology. Crit Rev Oncol Hematol
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Environmental components of mobility disability in community-living older persons. J Am Geriatr Soc
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Handgrip strength and cause-specific and total mortality in older disabled women: exploring the mechanism. J Am Geriatr Soc
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Assessing the building blocks of function: utilizing measures of functional limitation. Am J Prev Med
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100 4.212 2003
Age and disability affect dietary intake. J Nutr
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29 4.145 2003
Aging bone in men and women: beyond changes in bone mineral density. Osteoporos Int
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56 3.591 2003
Is chronic inflammation a determinant of blood pressure in the elderly? Am J Hypertens
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18 3.541 2003
Serum IL-1beta levels in health and disease: a population-based study. 'The InCHIANTI study'. Cytokine
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28 3.488 2003
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Association between the HLA-DR alleles and longevity: a study in Sardinian population. Exp Gerontol
12581796
9 3.34 2003
The MALVA (MAntova LongeVA) study: an investigation on people 98 years of age and over in a province of Northern Italy. Exp Gerontol
14580872
3 3.34 2003
High-frequency vibration training increases muscle power in postmenopausal women. Arch Phys Med Rehabil
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52 3.289 2003
Blood pressure, arterial function, structure, and aging: the role of hormonal replacement therapy in postmenopausal women. J Clin Hypertens (Greenwich)
12826785
7 3.242 2003
Nursing home case-mix instruments: validation of the RUG-III system in Italy. Aging Clin Exp Res
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4 1.394 2003
Sex-related differences in the length of disability prior to death in older persons. Aging Clin Exp Res
14661822
14 1.394 2003
Risks for frequent antimicrobial-treated infections in postmenopausal women. Aging Clin Exp Res
12841413
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Comorbidities and impairments explaining the association between diabetes and lower extremity disability: The Women's Health and Aging Study. Diabetes Care
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70 11.857 2002
Influence of calcium-sensing receptor gene on urinary calcium excretion in stone-forming patients. J Am Soc Nephrol
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41 8.966 2002
The ankle brachial index and change in lower extremity functioning over time: the Women's Health and Aging Study. J Am Geriatr Soc
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16 4.388 2002
Underestimation of disability occurrence in epidemiological studies of older people: is research on disability still alive? J Am Geriatr Soc
12383164
20 4.388 2002
The "Oldest Man on the Planet". J Am Geriatr Soc
12473030
2 4.388 2002
Myostatin polymorphisms and age-related sarcopenia in the Italian population. J Am Geriatr Soc
12165013
19 4.388 2002
Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons. J Am Geriatr Soc
11982663
117 4.388 2002
The effect of cardiovascular and osteoarticular diseases on disability in older Italian men and women: rationale, design, and sample characteristics of the Progetto Veneto Anziani (PRO.V.A.) study. J Am Geriatr Soc
12383151
17 4.388 2002
Low serum vitamin d does not predict new disability or loss of muscle strength in older women. J Am Geriatr Soc
12028180
38 4.388 2002
Lower extremity performance is associated with daily life physical activity in individuals with and without peripheral arterial disease. J Am Geriatr Soc
12028205
22 4.388 2002
Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels. J Am Geriatr Soc
12473005
226 4.388 2002
Geriatric Index of Comorbidity: validation and comparison with other measures of comorbidity. Age Ageing
12147566
43 4.282 2002
Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons. Am J Physiol Endocrinol Metab
12419777
103 4.142 2002
Biomarkers of frailty in older persons. J Endocrinol Invest
12508906
54 2.633 2002
A role for sarcopenia in late-life osteoporosis. Aging Clin Exp Res
12027146
7 1.394 2002
Understanding the physiological and functional consequences of menopause: the PROSALMEN study. PROgetto SALute MENopausa. Aging Clin Exp Res
12387523
0 1.394 2002
Changes in anthropometric measures in men and women across the life-span: findings from the InCHIANTI study. Soz Praventivmed
12512227
13 0 2002
Environmental demands associated with community mobility in older adults with and without mobility disabilities. Phys Ther
12088464
72 0 2002
Who should be screened for osteoporosis? JAMA
11667923
0 44.405 2001
Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study. Circulation
11181468
132 19.309 2001
Treatment of isolated systolic hypertension is most effective in older patients with high-risk profile. Circulation
11602495
9 19.309 2001
New aspects of the insulin resistance syndrome: impact on haematological parameters. Diabetologia
11692171
42 6.08 2001
Measuring higher level physical function in well-functioning older adults: expanding familiar approaches in the Health ABC study. J Gerontol A Biol Sci Med Sci
11584038
252 5.957 2001
Dementia and disability outcomes in large hypertension trials: lessons learned from the systolic hypertension in the elderly program (SHEP) trial. Am J Epidemiol
11159149
52 4.825 2001
Coimpairments as predictors of severe walking disability in older women. J Am Geriatr Soc
11207838
58 4.388 2001
Progressive versus catastrophic loss of the ability to walk: implications for the prevention of mobility loss. J Am Geriatr Soc
11890584
43 4.388 2001
Severity of upper and lower extremity functional limitation: scale development and validation with self-report and performance-based measures of physical function. WHAS Research Group. Women's Health and Aging Study. J Gerontol B Psychol Sci Soc Sci
11192340
28 3.064 2001
Y chromosome binary markers to study the high prevalence of males in Sardinian centenarians and the genetic structure of the Sardinian population. Hum Hered
11588396
10 1.216 2001
Mild cognitive impairment: clinical features and review of screening instruments. Aging (Milano)
11442301
10 0 2001
Summarizing amount of difficulty in ADLs: a refined characterization of disability. Results from the women's health and aging study. Aging (Milano)
11845974
9 0 2001
Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women's Health and Aging Study. Am J Psychiatry
10784463
62 14.176 2000
Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci
10811152
1151 5.957 2000
Lower extremity performance in nondisabled older persons as a predictor of subsequent hospitalization. J Gerontol A Biol Sci Med Sci
11078100
152 5.957 2000
Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci
11129392
150 5.957 2000
A new method for identifying antibiotic-treated infections using automated pharmacy records. J Clin Epidemiol
11027941
1 4.978 2000
Prevalence of symptomatic hand osteoarthritis in community-dwelling older persons: the ICARe Dicomano study. Insufficienza Cardiaca negli Anzizni Residenti a Dicomano. Osteoarthritis Cartilage
11156485
6 4.742 2000
Subsystems contributing to the decline in ability to walk: bridging the gap between epidemiology and geriatric practice in the InCHIANTI study. J Am Geriatr Soc
11129752
478 4.388 2000
The prognostic value of serum albumin in healthy older persons with low and high serum interleukin-6 (IL-6) levels. J Am Geriatr Soc
11083315
16 4.388 2000
Physical inactivity and smoking increase risk for serious infections in older women. J Am Geriatr Soc
11129746
3 4.388 2000
True osteoporosis and frailty-related osteopenia: two different clinical entities. J Am Geriatr Soc
11129773
10 4.388 2000
The protective effect of emotional vitality on adverse health outcomes in disabled older women. J Am Geriatr Soc
11083309
31 4.388 2000
Characteristics of nondisabled older persons who perform poorly in objective tests of lower extremity function. J Am Geriatr Soc
10983911
48 4.388 2000
Disease severity and health-related quality of life across different chronic conditions. J Am Geriatr Soc
11083330
17 4.388 2000
Apo E genotype, diabetes, and peripheral arterial disease in older men: the Honolulu Asia-aging study. Genet Epidemiol
10861896
6 1.884 2000
Active life expectancy from annual follow-up data with missing responses. Biometrics
10783802
11 1.329 2000
Do men and women follow different trajectories to reach extreme longevity? Italian Multicenter Study on Centenarians (IMUSCE). Aging (Milano)
10902049
61 0 2000
Preventive health care for older women: life-style recommendations and new directions. Aging (Milano)
10902053
0 0 2000
P53 codon 72 polymorphism and longevity: additional data on centenarians from continental Italy and Sardinia. Am J Hum Genet
10577935
9 9.025 1999
Coimpairments: strength and balance as predictors of severe walking disability. J Gerontol A Biol Sci Med Sci
10219007
30 5.957 1999
New and worsening conditions and change in physical and cognitive performance during weekly evaluations over 6 months: the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci
10496547
11 5.957 1999
Low back pain and disability in older women: independent association with difficulty but not inability to perform daily activities. J Gerontol A Biol Sci Med Sci
10568530
46 5.957 1999
Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med
10335721
473 5.55 1999
Smoking, physical activity, and active life expectancy. Am J Epidemiol
10192312
77 4.825 1999
Aging successfully until death in old age: opportunities for increasing active life expectancy. Am J Epidemiol
10192313
54 4.825 1999
Heart failure in community-dwelling older persons: aims, design and adherence rate of the ICARe Dicomano project: an epidemiologic study. Insufficienza Cardiaca negli Anziani Residenti a Dicomano. J Am Geriatr Soc
10366164
7 4.388 1999
Serum IL-6 level and the development of disability in older persons. J Am Geriatr Soc
10366160
300 4.388 1999
Hand-grip strength predicts incident disability in non-disabled older men. Age Ageing
10475865
122 4.282 1999
Exploring the effect of depression on physical disability: longitudinal evidence from the established populations for epidemiologic studies of the elderly. Am J Public Health
10474551
152 3.858 1999
Lower body osteoarticular pain and dose of analgesic medications in older disabled women: the Women's Health and Aging Study. Am J Public Health
10358691
20 3.858 1999
Evidence for a black-white crossover in all-cause and coronary heart disease mortality in an older population: the North Carolina EPESE. Am J Public Health
10076478
30 3.858 1999
Kinematic characteristics of standing disequilibrium: reliability and validity of a posturographic protocol. Arch Phys Med Rehabil
10084435
24 3.289 1999
AKEntAnnos. The Sardinia Study of Extreme Longevity. Aging (Milano)
10476308
26 0 1999
Measuring muscular strength of the lower limbs by hand-held dynamometer: a standard protocol. Aging (Milano)
10631877
56 0 1999
Factors related to the length of in-hospital stay of geriatric patients. Aging (Milano)
10476309
8 0 1999
Cigarette smoke exposure and hearing loss. JAMA
9749471
1 44.405 1998
Depressive symptoms and physical decline in community-dwelling older persons. JAMA
9624025
188 44.405 1998
Chronically depressed mood and cancer risk in older persons. J Natl Cancer Inst
9862626
82 12.589 1998
Therapeutic choice with regard to life expectancy and cost benefit analysis in cancer diagnosis and treatment. Crit Rev Oncol Hematol
9571311
0 4.971 1998
Foot pain and disability in older women. Am J Epidemiol
9778172
48 4.825 1998
Short-term consistency in self-reported physical functioning among elderly women: the Women's Health and Aging Study. Am J Epidemiol
9554418
12 4.825 1998
Emotional vitality among disabled older women: the Women's Health and Aging Study. J Am Geriatr Soc
9670865
16 4.388 1998
Constant hierarchic patterns of physical functioning across seven populations in five countries. Gerontologist
9640848
28 3.505 1998
Black/white differences in the relationship between MMSE scores and disability: the Women's Health and Aging Study. J Gerontol B Psychol Sci Soc Sci
9602835
25 3.064 1998
Is self-rated health comparable across cultures and genders? J Gerontol B Psychol Sci Soc Sci
9602839
106 3.064 1998
Association of muscle strength with maximum walking speed in disabled older women. Am J Phys Med Rehabil
9715919
52 1.734 1998
Characteristics of geriatric patients related to early and late readmissions to hospital. Aging (Milano)
9825026
12 0 1998
Diuretic-based treatment and cardiovascular events in patients with mild renal dysfunction enrolled in the systolic hypertension in the elderly program. Arch Intern Med
9645829
11 0 1998
Is the telephone interview for cognitive status a valid alternative in persons who cannot be evaluated by the Mini Mental State Examination? Aging (Milano)
9825025
33 0 1998
Aims, design and enrollment rate of the Cardiac Rehabilitation in Advanced Age (CR-AGE) randomized, controlled trial. Aging (Milano)
9932140
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Hospital diagnoses, Medicare charges, and nursing home admissions in the year when older persons become severely disabled. JAMA
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89 44.405 1997
Clarifying the direct relation between total cholesterol levels and death from coronary heart disease in older persons. Ann Intern Med
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39 17.202 1997
Apolipoprotein E epsilon 2 allele and risk of stroke in the older population. Stroke
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Departures from linearity in the relationship between measures of muscular strength and physical performance of the lower extremities: the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci
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Item re-scaling of an Italian version of the sickness impact profile: effect of age and profession of the observers. J Clin Epidemiol
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Who are the older patients failing to recover mobility after rehabilitation? J Am Geriatr Soc
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The effect of chronic diseases on physical function. Comparison between activities of daily living scales and the Physical Performance Test. Age Ageing
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Validation of a multidimensional evaluation scale for use in elderly cancer patients. Cancer
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Progressive versus catastrophic disability: a longitudinal view of the disablement process. J Gerontol A Biol Sci Med Sci
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Cognitive impairment and risk of stroke in the older population. J Am Geriatr Soc
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Self-report of difficulty in performing functional activities identifies a broad range of disability in old age. J Am Geriatr Soc
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Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med
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Food intake and mortality in the frail elderly. J Gerontol A Biol Sci Med Sci
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Immediate and long-term survival after intra-aortic balloon pumping: is advanced age an independent, unfavorable prognostic factor? J Am Geriatr Soc
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Foot pain and disability in older persons: an epidemiologic survey. J Am Geriatr Soc
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Clinical Trials 33 Source:  ClinicalTrials

Synthesis

Principal Investigator: 7

By phase:

N/A 23
Phase 2 4
Phase 1 3
Phase 3 2

By status:

Completed 25
Recruiting 4
Active, not recruiting 2
Terminated 1

By Monocentric/Multicentric:

monocentric 26
multicentric2to4 5
multicentric5to9 0
multicentricup10 1

Main Topics

Cardiovascular Diseases 21
Nutritional and Metabolic Diseases 6
Endocrine System Diseases 4
Nervous System Diseases 4
Musculoskeletal Diseases 2

Cohort/Consortium Investigators 6

Drugs and Sponsors Source: ClinicalTrials

All Clinical Trials information

Clinical Trials Timeline Source: ClinicalTrials

Studies Phases and Years

Clinical Trials List Source: ClinicalTrials

Quick search selection

NCTID - Title Phase Status Year

NCT04228978

Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
N/A Recruiting 2020

NCT03065335

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated Dosed Ketamine Infusions in Major Depressive Disorder
Phase 1 Recruiting 2017

NCT02876887

Cocoa to Improve Walking Performance in Peripheral Artery Disease
N/A Completed 2017

NCT02593110

Telmisartan Plus Exercise to Improve Functioning in Peripheral Artery Disease
N/A Completed 2016

NCT02755584

Study of Skin Cells That Stop Replicating (Senescent) During Wound Healing
N/A Completed 2016

NCT02462824

Patient Centered Home Exercise Program for Peripheral Artery Disease
N/A Completed 2015

NCT02246660

RESveratrol To Improve Outcomes in oldeR pEople With PAD (the RESTORE Trial)
N/A Completed 2015

NCT02339012

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
N/A Recruiting 2015

NCT02538900

Low InTensity Exercise Intervention in PAD
N/A Completed 2015

NCT00233272

Baltimore Longitudinal Study of Aging
N/A Recruiting 2014

NCT01989793

A Study of Muscle Strength Maintenance in Older Adults
Phase 2 Completed 2013

NCT01517113

Age Related Changes in Body Composition
N/A Terminated 2012

NCT01402973

Pilot Study of a Dietary Intervention Based Upon Advanced Glycation End Products
N/A Completed 2011

NCT01408901

Treadmill Exercise and GM CSF Study to Improving Functioning in Peripheral Artery Disease (PAD)
N/A Completed 2011

NCT01323335

The Relationship Between Uric Acid and Inflammatory Markers
Phase 1 Completed 2009

NCT00693940

Effectiveness of Group Walking Sessions for Increasing Activity in People With Peripheral Arterial Disease (The Group Oriented Arterial Leg Study GOALS )
Phase 3 Completed 2008

NCT00520312

Magnetic Resonance Imaging to Identify Characteristics of Plaque Build Up in People With Peripheral Arterial Disease
N/A Completed 2007

NCT00378352

REVEAL Reduction of Infarct Expansion and Ventricular Remodeling With Erythropoietin After Large Myocardial Infarction
Phase 2 Completed 2005

NCT00104572

Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone Randomized Controlled Trial
Phase 2 Completed 2004

NCT00105066

The Effects of Metformin on Blood Vessel Structure and Function
Phase 2 Completed 2004

NCT00233311

Fast Food Study Assessment of the Effects of Fast Food on Inflammatory Markers
N/A Completed 2004

NCT00239707

GIP Glucose dependent Insulinotropic Peptide
Phase 1 Completed 2003

NCT01331512

The InChianti Follow Up Study
N/A Completed 2003

NCT00106327

Improving Functioning in Peripheral Arterial Disease
N/A Completed 2003

NCT00083369

Genetic and Environmental Determinants of Triglycerides (GOLDN)
N/A Completed 2002

NCT00005487

Multi Ethnic Study of Atherosclerosis (MESA)
N/A Active, not recruiting 1999

NCT00289237

Lifestyle Intervention in a General Population for Prevention of Ischaemic Heart Disease
N/A Completed 1999

NCT00005136

Family Heart Study (FHS)
N/A Completed 1992

NCT00005133

Cardiovascular Health Study (CHS)
N/A Active, not recruiting 1988

NCT00005131

Atherosclerosis Risk in Communities (ARIC)
N/A Completed 1985

NCT00005121

Framingham Heart Study
N/A Completed 1948

NCT00000611

Women s Health Initiative (WHI)
Phase 3 Completed 2024

LeadR Networks Source: Pubmed Source: ClinicalTrials

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Nb Contacts:
Country Contact count
United States 2537
Italy 420
United Kingdom 385
Germany 166
Netherlands 165
Canada 124
Sweden 105
Denmark 100
France 96
Finland 81
Australia 73
Spain 55
Switzerland 46
Japan 34
Norway 31
Belgium 28
Iceland 26
Ireland 22
Austria 20
India 20
Brazil 19
Greece 13
Czechia 12
Taiwan 12
Poland 11
Portugal 10
Estonia 9
New Zealand 8
Singapore 8
Turkey 7
Pakistan 6
Russia 6
Croatia 5
South Africa 5
Israel 4
Mexico 4
Saudi Arabia 4
Argentina 3
Egypt 3
Hungary 3
Iran 3
Philippines 3
Qatar 3
Sri Lanka 3
United Arab Emirates 3
Bulgaria 2
Cyprus 2
Kenya 2
Uruguay 2
Burkina Faso 1
Cameroon 1
Chile 1
Colombia 1
El Salvador 1
Jamaica 1
Lebanon 1
Lithuania 1
Luxembourg 1
Malawi 1
Malaysia 1
Maldives 1
Senegal 1
Seychelles 1
Slovakia 1
Slovenia 1
Sudan 1
Thailand 1
Uganda 1
Vietnam 1

LeadR Networks Source: Pubmed Source: ClinicalTrials

Graph connection

LeadR Networks Source: Pubmed Source: ClinicalTrials

Connection list

Name Organization Country Linked
Guralnik Jack M University of Maryland Medical Center United States 398
Bandinelli Stefania Azienda Usl Toscana Centro Italy 296
Simonsick Eleanor M National Institutes of Health United States 176
Resnick Susan M National Institutes of Health United States 143
Semba Richard D Johns Hopkins Hospital United States 141
Lauretani Fulvio University Hospitals Parma Medical Center United States 118
Mc Dermott Mary M Northwestern University (United States) United States 117
Criqui Michael H University of California System United States 102
Studenski Stephanie A University of Pittsburgh United States 81
Fried Linda P Columbia University Medical Center United States 81
Schrack Jennifer A Johns Hopkins Hospital United States 78
Metter E Jeffrey University of Tennessee Health Science Center United States 72
Maggio Marcello University Hospitals Parma Medical Center United States 68
Liu Kiang Northwestern University (United States) United States 68
Cherubini Antonio Istituto Nazionale di Riposo e Cura per Anziani Italy 60
Shardell Michelle University of Maryland, Baltimore United States 59
Melzer David University of Exeter United Kingdom 55
Kibbe Melina R University of Virginia Health System United States 52
Tian Qu National Institute on Aging United States 52
Moaddel Ruin National Institute on Aging United States 51
Egan Josephine M National Institutes of Health United States 46
Volpato Stefano Arcispedale Sant'Anna Italy 45
Chia Chee W National Institutes of Health United States 45
Harris Tamara B National Institute on Aging United States 45
Milaneschi Yuri Amsterdam University Medical Center Netherlands 39