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LeadR Profile


Josep M Argilés
University of Barcelona
Spain

SLR Biochemistry ScienceLeadR Reputation 100%

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Health Specialties

Main specialty  Biochemistry
Full career - Last 3 years

Main Topics

Publications and Clinical Trials


Publications - Clinical Trials

Education

Academic Background

Source: ORCID

Organization

all information about organizations

Source: Pubmed

University of Barcelona

Awards and Honors

Source: ORCID

Academic Societies

Source: ORCID

Publications Synthesis

Source: Pubmed

Number : 330

Citations

Citations: 7 835 1st author: 91 Last author: 141 Unique author: 5

Main journals

Cancer Lett 24
J Cachexia Sarcopenia Muscle 15
FEBS Lett 14
Clin Nutr 12
Int J Mol Med 11

Best Journals

Nat Rev Cancer 1
Nat Rev Clin Oncol 1

Breakdown by type

Historic per year



Main pathologies and trends

Publications List

Quick search selection

Source: Pubmed Source: OpenAlex
Title Journal CIT SLR Year
Formoterol reduces muscle wasting in mice undergoing doxorubicin chemotherapy. Front Oncol
38234397
0 4.7 2024
Cancer-associated cachexia - understanding the tumour macroenvironment and microenvironment to improve management. Nat Rev Clin Oncol
36806788
16 78.8 2023
Effects of S-pindolol in mouse pancreatic and lung cancer cachexia models. J Cachexia Sarcopenia Muscle
37130578
1 8.9 2023
Effect of Cancer-Related Cachexia and Associated Changes in Nutritional Status, Inflammatory Status, and Muscle Mass on Immunotherapy Efficacy and Survival in Patients with Advanced Non-Small Cell Lung Cancer. Cancers (Basel)
36831431
4 5.2 2023
The atypical β-blocker S-oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model. J Cachexia Sarcopenia Muscle
36346141
3 8.9 2022
Effects of Cigarette Smoke on Adipose and Skeletal Muscle Tissue: In Vivo and In Vitro Studies. Cells
36139468
5 6 2022
Lack of Synergy Between β-Agonist Treatment and a Blockage of Sarcoplasmic Calcium Flow in a Rat Cancer Cachexia Model. Onco Targets Ther
33762827
0 4.345 2021
Win 55,212-2, atenolol and subdiaphragmatic vagotomy prevent acceleration of gastric emptying induced by cachexia via Yoshida-AH-130 cells in rats. Eur J Pharmacol
32234430
3 4.432 2020
Laparoscopic Right Adrenalectomy in a Large Right Adrenal Oncocytic Carcinoma. Ann Surg Oncol
33244737
0 4.339 2020
Labour accidents and financial performance: empirical analysis of the type of relationship in the Spanish context. Int J Occup Saf Ergon
33198588
0 0.01 2020
Differential structural features in soleus and gastrocnemius of carnitine-treated cancer cachectic rats. J Cell Physiol
31241186
7 6.384 2019
Autophagy Exacerbates Muscle Wasting in Cancer Cachexia and Impairs Mitochondrial Function. J Mol Biol
31150737
40 4.76 2019
A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice. Int J Mol Sci
31600911
3 4.556 2019
Mediators of cachexia in cancer patients. Nutrition
31177056
28 3.769 2019
Cancer cachexia, a clinical challenge. Curr Opin Oncol
30893144
9 3.336 2019
Therapeutic strategies against cancer cachexia. Eur J Transl Myol
31019661
24 0 2019
The animal cachexia score (ACASCO). Animal Model Exp Med
31773096
5 0 2019
Inter-tissue communication in cancer cachexia. Nat Rev Endocrinol
30464312
101 24.646 2018
Effects of the beta agonist formoterol on atrophy signaling, autophagy, and muscle phenotype in respiratory and limb muscles of rats with cancer-induced cachexia. Biochimie
29654866
21 3.418 2018
Editorial: Biological Mechanism-Based and Patient-Centered Management of Cancer-Related Symptoms and Syndromes. Front Physiol
30618829
2 3.151 2018
Unifying diagnostic criteria for cachexia: An urgent need. Clin Nutr
28238466
5 5.496 2017
Novel targeted therapies for cancer cachexia. Biochem J
28751550
26 3.857 2017
A Rat Immobilization Model Based on Cage Volume Reduction: A Physiological Model for Bed Rest? Front Physiol
28424626
6 3.325 2017
Validation of the CAchexia SCOre (CASCO). Staging Cancer Patients: The Use of miniCASCO as a Simplified Tool. Front Physiol
28261113
19 3.325 2017
Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats. PeerJ
29255650
14 2.118 2017
The Three Faces of Sarcopenia. J Am Med Dir Assoc
27161851
5 5.775 2016
Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease. J Am Med Dir Assoc
27324808
156 5.775 2016
The 2015 ESPEN Sir David Cuthbertson lecture: Inflammation as the driving force of muscle wasting in cancer. Clin Nutr
27268093
11 5.496 2016
The assessment of productivity in biomedical research. Ann Med
27649468
0 3.715 2016
A multifactorial anti-cachectic approach for cancer cachexia in a rat model undergoing chemotherapy. J Cachexia Sarcopenia Muscle
27066318
31 9.697 2015
Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes. J Cachexia Sarcopenia Muscle
27065075
27 9.697 2015
Open source in cachexia? J Cachexia Sarcopenia Muscle
26136418
0 9.697 2015
Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling. J Cachexia Sarcopenia Muscle
26136415
20 9.697 2015
Request for regulatory guidance for cancer cachexia intervention trials. J Cachexia Sarcopenia Muscle
26675232
57 9.697 2015
Experimental cancer cachexia: Evolving strategies for getting closer to the human scenario. Semin Cell Dev Biol
26343953
34 6.614 2015
Complete reversal of muscle wasting in experimental cancer cachexia: Additive effects of activin type II receptor inhibition and β-2 agonist. Int J Cancer
26595367
30 6.513 2015
Cachexia and sarcopenia: mechanisms and potential targets for intervention. Curr Opin Pharmacol
25974750
108 5.363 2015
Combination of exercise training and erythropoietin prevents cancer-induced muscle alterations. Oncotarget
26636649
54 5.008 2015
Muscle wasting in cancer: the role of mitochondria. Curr Opin Clin Nutr Metab Care
25769061
32 4.023 2015
Nonmuscle Tissues Contribution to Cancer Cachexia. Mediators Inflamm
26523094
22 3.232 2015
Cancer cachexia: understanding the molecular basis. Nat Rev Cancer
25291291
519 37.147 2014
Cachexia: a problem of energetic inefficiency. J Cachexia Sarcopenia Muscle
25118829
40 9.697 2014
Formoterol in the treatment of experimental cancer cachexia: effects on heart function. J Cachexia Sarcopenia Muscle
25167857
23 9.697 2014
Distinct behaviour of sorafenib in experimental cachexia-inducing tumours: the role of STAT3. PLoS One
25436606
14 3.706 2014
A differential pattern of gene expression in skeletal muscle of tumor-bearing rats reveals dysregulation of excitation–contraction coupling together with additional muscle alterations. Muscle Nerve
23649607
9 2.605 2014
Prevention of liver cancer cachexia-induced cardiac wasting and heart failure. Eur Heart J
23990596
88 20.212 2013
Hypothalamic food intake regulation in a cancer-cachectic mouse model. J Cachexia Sarcopenia Muscle
24222472
12 9.697 2013
Erythropoietin administration partially prevents adipose tissue loss in experimental cancer cachexia models. J Lipid Res
23966665
12 4.81 2013
A new look at an old drug for the treatment of cancer cachexia: megestrol acetate. Clin Nutr
23395103
17 4.548 2013
Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model. Int J Oncol
23817738
53 3.079 2013
Mitochondrial and sarcoplasmic reticulum abnormalities in cancer cachexia: altered energetic efficiency? Biochim Biophys Acta
23200745
50 0 2013
Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways. Gastroenterology
23142626
40 18.392 2012
Are there any benefits of exercise training in cancer cachexia? J Cachexia Sarcopenia Muscle
22565649
47 9.697 2012
Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia. Int J Cancer
22336965
26 6.513 2012
Myostatin: more than just a regulator of muscle mass. Drug Discov Today
22342983
47 6.369 2012
L-Carnitine: an adequate supplement for a multi-targeted anti-wasting therapy in cancer. Clin Nutr
22608917
18 4.548 2012
The potential of ghrelin in the treatment of cancer cachexia. Expert Opin Biol Ther
23078025
15 3.684 2012
Mechanisms and treatment of cancer cachexia. Nutr Metab Cardiovasc Dis
22749678
21 3.679 2012
Theophylline is able to partially revert cachexia in tumour-bearing rats. Nutr Metab (Lond)
22909172
13 2.974 2012
A high fat diet in CF-1 mice: An experimental model for metabolic syndrome. Mol Med Rep
21479424
2 1.692 2012
Counteracting inflammation: a promising therapy in cachexia. Crit Rev Oncog
22831156
31 1.429 2012
The cachexia score (CASCO): a new tool for staging cachectic cancer patients. J Cachexia Sarcopenia Muscle
21766054
60 9.697 2011
Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise. J Cachexia Sarcopenia Muscle
21766055
40 9.697 2011
Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance. J Cachexia Sarcopenia Muscle
22450815
62 9.697 2011
Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats: a role in impaired regeneration? J Cachexia Sarcopenia Muscle
21475674
14 9.697 2011
Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc
21640657
337 5.775 2011
Anti-inflammatory therapies in cancer cachexia. Eur J Pharmacol
21835173
33 2.896 2011
Cancer cachexia: physical activity and muscle force in tumour-bearing rats. Oncol Rep
21109976
19 2.662 2011
Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice. Oncol Rep
21503587
22 2.662 2011
Effects of formoterol on protein metabolism in myotubes during hyperthermia. Muscle Nerve
21254094
3 2.605 2011
Interleukin-15 affects differentiation and apoptosis in adipocytes: implications in obesity. Lipids
21894465
9 1.934 2011
Formoterol treatment downregulates the myostatin system in skeletal muscle of cachectic tumour-bearing rats. Oncol Lett
22740878
8 1.39 2011
Formoterol and cancer muscle wasting in rats: Effects on muscle force and total physical activity. Exp Ther Med
22977567
8 1.261 2011
Redox balance and carbonylated proteins in limb and heart muscles of cachectic rats. Antioxid Redox Signal
19737087
30 6.337 2010
Consensus on cachexia definitions. J Am Med Dir Assoc
20439040
44 5.775 2010
Nutritional recommendations for the management of sarcopenia. J Am Med Dir Assoc
20627179
177 5.775 2010
Nutraceutical inhibition of muscle proteolysis: a role of diallyl sulphide in the treatment of muscle wasting. Clin Nutr
20655130
1 4.548 2010
Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics". Clin Nutr
20060626
503 4.548 2010
Megestrol acetate: its impact on muscle protein metabolism supports its use in cancer cachexia. Clin Nutr
20621398
8 4.548 2010
Effects of eicosapentaenoic acid (EPA) treatment on insulin sensitivity in an animal model of diabetes: improvement of the inflammatory status. Obesity (Silver Spring)
20885391
37 3.873 2010
Patterns of gene expression in muscle and fat in tumor-bearing rats: effects of CRF2R agonist on cachexia. Muscle Nerve
21104868
2 2.605 2010
Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia. Int J Mol Med
21069263
45 2.341 2010
Optimal management of cancer anorexia-cachexia syndrome. Cancer Manag Res
21188094
16 0 2010
Direct effects of doxorubicin on skeletal muscle contribute to fatigue. Br J Cancer
19165199
53 6.176 2009
Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice. Br J Cancer
19259092
47 6.176 2009
Impaired immune function: an early marker for cancer cachexia. Oncol Rep
19885593
11 2.662 2009
Interleukin-15 increases calcineurin expression in 3T3-L1 cells: possible involvement on in vivo adipocyte differentiation. Int J Mol Med
19724884
14 2.341 2009
PPARdelta mediates IL15 metabolic actions in myotubes: effects of hyperthermia. Int J Mol Med
19513536
4 2.341 2009
The role of cytokines in cancer cachexia. Curr Opin Support Palliat Care
19713854
85 2.045 2009
Both AP-1 and NF-kappaB seem to be involved in tumour growth in an experimental rat hepatoma. Anticancer Res
19414381
5 1.937 2009
Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity. Drug Discov Today
19041416
22 6.369 2008
Beneficial immune modulatory effects of a specific nutritional combination in a murine model for cancer cachexia. Br J Cancer
19018259
23 6.176 2008
Cachexia: a new definition. Clin Nutr
18718696
776 4.548 2008
Oversecretion of interleukin-15 from skeletal muscle reduces adiposity. Am J Physiol Endocrinol Metab
19001550
112 4.142 2008
Effects of IL-15 on rat brown adipose tissue: uncoupling proteins and PPARs. Obesity (Silver Spring)
18239634
25 3.873 2008
UCP3 overexpression neutralizes oxidative stress rather than nitrosative stress in mouse myotubes. FEBS Lett
19101552
13 3.623 2008
Apoptosis signalling is essential and precedes protein degradation in wasting skeletal muscle during catabolic conditions. Int J Biochem Cell Biol
18329944
23 3.505 2008
Effects of the PPARgamma agonist GW1929 on muscle wasting in tumour-bearing mice. Oncol Rep
18097603
4 2.662 2008
Effects of CRF2R agonist on tumor growth and cachexia in mice implanted with Lewis lung carcinoma cells. Muscle Nerve
17912749
13 2.605 2008
Are peroxisome proliferator-activated receptors involved in skeletal muscle wasting during experimental cancer cachexia? Role of beta2-adrenergic agonists. Cancer Res
17616713
16 9.122 2007
Novel approaches to the treatment of cachexia. Drug Discov Today
18190867
21 6.369 2007
Antiproteolytic effects of plasma from hibernating bears: a new approach for muscle wasting therapy? Clin Nutr
17904252
20 4.548 2007
Protein breakdown on whole-body and organ level in non-cachectic tumour-bearing mice undergoing surgery. Clin Nutr
17513024
1 4.548 2007
Apoptosis is present in skeletal muscle of cachectic gastro-intestinal cancer patients. Clin Nutr
17688974
28 4.548 2007
Resveratrol does not ameliorate muscle wasting in different types of cancer cachexia models. Clin Nutr
17261345
16 4.548 2007
The AP-1/NF-kappaB double inhibitor SP100030 can revert muscle wasting during experimental cancer cachexia. Int J Oncol
17390027
16 3.079 2007
Emerging drugs for cancer cachexia. Expert Opin Emerg Drugs
17979599
3 3.062 2007
Potassium channels are a new target field in anticancer drug design. Recent Pat Anticancer Drug Discov
18221064
18 2.956 2007
Targets in clinical oncology: the metabolic environment of the patient. Front Biosci
17485280
5 2.497 2007
Mechanisms to explain wasting of muscle and fat in cancer cachexia. Curr Opin Support Palliat Care
18685378
14 2.045 2007
Modulations of the calcineurin/NF-AT pathway in skeletal muscle atrophy. Biochim Biophys Acta
17442496
3 0 2007
Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity. Endocr Rev
16556851
5 15.745 2006
Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model. Cancer Lett
16466851
28 6.375 2006
The AP-1/CJUN signaling cascade is involved in muscle differentiation: implications in muscle wasting during cancer cachexia. FEBS Lett
16412434
13 3.623 2006
IGF-1 is downregulated in experimental cancer cachexia. Am J Physiol Regul Integr Comp Physiol
16614058
72 2.982 2006
BARD1 content correlates with increased DNA fragmentation associated with muscle wasting in tumour-bearing rats. Oncol Rep
16685375
4 2.662 2006
Training depletes muscle glutathione in patients with chronic obstructive pulmonary disease and low body mass index. Respiration
16825756
12 2.543 2006
Hemostasis alterations in metabolic syndrome (review). Int J Mol Med
17016629
23 2.341 2006
[Physiology of sarcopenia. Similarities and differences with neoplasic cachexia (muscle impairments in cancer and ageing)]. Nutr Hosp
16768029
2 0.747 2006
[Pathophysiology of neoplasic cachexia]. Nutr Hosp
16768025
8 0.747 2006
Cytokines as mediators and targets for cancer cachexia. Cancer Treat Res
16610709
14 0 2006
Interleukin-15 increases glucose uptake in skeletal muscle. An antidiabetogenic effect of the cytokine. Biochim Biophys Acta
17056184
36 0 2006
Muscle wasting in cancer and ageing: cachexia versus sarcopenia. Adv Gerontol
16676797
16 0 2006
Effects of interleukin-15 on lipid oxidation: disposal of an oral [(14)C]-triolein load. Biochim Biophys Acta
16458591
28 0 2006
Cross-talk between skeletal muscle and adipose tissue: a link with obesity? Med Res Rev
15389734
53 8.763 2005
Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats. FEBS Lett
15757655
50 3.623 2005
Activation of UCPs gene expression in skeletal muscle can be independent on both circulating fatty acids and food intake. Involvement of ROS in a model of mouse cancer cachexia. FEBS Lett
15670834
25 3.623 2005
The pivotal role of cytokines in muscle wasting during cancer. Int J Biochem Cell Biol
15878837
10 3.505 2005
The pivotal role of cytokines in muscle wasting during cancer. Int J Biochem Cell Biol
16105746
36 3.505 2005
Skeletal muscle wasting in tumor-bearing rats is associated with MyoD down-regulation. Int J Oncol
15870883
10 3.079 2005
Cancer cachexia results in an increase in TNF-alpha receptor gene expression in both skeletal muscle and adipose tissue. Int J Oncol
16077938
12 3.079 2005
Systemic inflammation correlates with increased expression of skeletal muscle ubiquitin but not uncoupling proteins in cancer cachexia. Oncol Rep
15944798
30 2.662 2005
Interleukin-15 decreases lipid intestinal absorption. Int J Mol Med
15870900
3 2.341 2005
Interleukin-15 decreases proteolysis in skeletal muscle: a direct effect. Int J Mol Med
16077957
24 2.341 2005
Mediators involved in the cancer anorexia-cachexia syndrome: past, present, and future. Nutrition
16043325
34 2.195 2005
Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: evidence for a skeletal muscle-to-fat signaling pathway. Cell Biol Int
15951205
65 1.831 2005
Cancer-associated malnutrition. Eur J Oncol Nurs
16437757
87 1.826 2005
Overexpression of UCP3 in both murine and human myotubes is linked with the activation of proteolytic systems: a role in muscle wasting? Biochim Biophys Acta
16337086
3 0 2005
Anticachectic effects of formoterol: a drug for potential treatment of muscle wasting. Cancer Res
15374990
53 9.122 2004
Interleukin-15 is able to suppress the increased DNA fragmentation associated with muscle wasting in tumour-bearing rats. FEBS Lett
15225634
35 3.623 2004
The systemic inflammatory response is involved in the regulation of K(+) channel expression in brain via TNF-alpha-dependent and -independent pathways. FEBS Lett
15304346
8 3.623 2004
Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia. Int J Biochem Cell Biol
15743680
61 3.505 2004
Adipocyte expression and circulating levels of leptin increase in both gynaecological and breast cancer patients. Int J Oncol
15138597
46 3.079 2004
The pharmacological treatment of cachexia. Curr Drug Targets
15058312
10 3.061 2004
Plasma from pregnant rats has anti-tumoural activity. Oncol Rep
15375517
0 2.662 2004
Sepsis induces DNA fragmentation in rat skeletal muscle. Eur Cytokine Netw
14715419
5 2.364 2004
Effect of c-ski overexpression on the development of cachexia in mice bearing the Lewis lung carcinoma. Int J Mol Med
15375607
2 2.341 2004
Rat liver lipogenesis is modulated by interleukin-15. Int J Mol Med
15138618
7 2.341 2004
Increased tumour necrosis factor-alpha plasma levels during moderate-intensity exercise in COPD patients. Eur Respir J
12765422
38 10.569 2003
Mice lacking TNFalpha receptors 1 and 2 are resistant to death and fulminant liver injury induced by agonistic anti-Fas antibody. Cell Death Differ
12934074
18 8.339 2003
Reduced protein degradation rates and low expression of proteolytic systems support skeletal muscle hypertrophy in transgenic mice overexpressing the c-ski oncogene. Cancer Lett
14568169
3 6.375 2003
Catabolic mediators as targets for cancer cachexia. Drug Discov Today
12963320
5 6.369 2003
Cytokines in the pathogenesis of cancer cachexia. Curr Opin Clin Nutr Metab Care
12806213
58 4.023 2003
Impaired voltage-gated K+ channel expression in brain during experimental cancer cachexia. FEBS Lett
12586336
8 3.623 2003
Cancer cachexia: the molecular mechanisms. Int J Biochem Cell Biol
12565701
31 3.505 2003
Tumour necrosis factor-alpha uncouples respiration in isolated rat mitochondria. Cytokine
12946099
10 3.488 2003
Muscle ubiquitin m-rNA levels in patients with end-stage renal disease on maintenance hemodialysis. J Nephrol
12455723
4 2.153 2003
[Congenital absence of the inferior vena cava as a risk factor for pulmonar thromboembolism]. An Med Interna
12911014
0 0 2003
TNF-alpha modulates cytokine and cytokine receptors in C2C12 myotubes. Cancer Lett
11741746
12 6.375 2002
Effects of the phosphodiesterase-IV inhibitor EMD 95832/3 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma. Cancer Lett
12406548
0 6.375 2002
TNF-alpha is involved in activating DNA fragmentation in skeletal muscle. Br J Cancer
11953838
19 6.176 2002
Branched-chain amino acids: a role in skeletal muscle proteolysis in catabolic states? J Cell Physiol
12012323
7 4.08 2002
Overexpression of interleukin-15 induces skeletal muscle hypertrophy in vitro: implications for treatment of muscle wasting disorders. Exp Cell Res
12372339
58 3.546 2002
The role of uncoupling proteins in pathophysiological states. Biochem Biophys Res Commun
12054495
27 2.466 2002
Direct effects of tumor necrosis factor alpha (TNF-alpha) on murine skeletal muscle cell lines. Bimodal effects on protein metabolism. Eur Cytokine Netw
11566620
6 2.364 2002
Tumor necrosis factor-alpha exerts interleukin-6-dependent and -independent effects on cultured skeletal muscle cells. Biochim Biophys Acta
11853880
17 0 2002
Effects of interleukin-15 (IL-15) on adipose tissue mass in rodent obesity models: evidence for direct IL-15 action on adipose tissue. Biochim Biophys Acta
11960686
35 0 2002
TNFalpha expression of subcutaneous adipose tissue in obese and morbid obese females: relationship to adipocyte LPL activity and leptin synthesis. Int J Obes Relat Metab Disord
12032749
25 0 2002
Reduced muscle redox capacity after endurance training in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med
11673195
23 13.204 2001
Cancer cachexia: a therapeutic approach. Med Res Rev
11135301
18 8.763 2001
Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model. Cancer Lett
11323096
23 6.375 2001
Hyperlipemia: a role in regulating UCP3 gene expression in skeletal muscle during cancer cachexia? FEBS Lett
11566186
8 3.623 2001
Insulin and cancer (Review). Int J Oncol
11251161
26 3.079 2001
Increased muscle ubiquitin mRNA levels in gastric cancer patients. Am J Physiol Regul Integr Comp Physiol
11294777
35 2.982 2001
Metabolic interrelationships between liver and skeletal muscle in pathological states. Life Sci
11531159
6 2.936 2001
Hepatic transport of gluconeogenic substrates during tumor growth in the rat. Cancer Invest
11338881
0 2.39 2001
Increased uncoupling protein-2 gene expression in brain of lipopolysaccharide-injected mice: role of tumour necrosis factor-alpha? Biochim Biophys Acta
11341972
7 0 2001
Interleukin-15 mediates reciprocal regulation of adipose and muscle mass: a potential role in body weight control. Biochim Biophys Acta
11287118
47 0 2001
LPS induces apoptosis in macrophages mostly through the autocrine production of TNF-alpha. Blood
10845916
105 13.164 2000
Lack of effect of the cytokine suppressive agent FR167653 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma. Cancer Lett
10893448
1 6.375 2000
Interleukin-15 antagonizes muscle protein waste in tumour-bearing rats. Br J Cancer
10945502
49 6.176 2000
Short-term effects of leptin on skeletal muscle protein metabolism in the rat. J Nutr Biochem
11091097
9 4.518 2000
Branched-chain amino acids inhibit proteolysis in rat skeletal muscle: mechanisms involved. J Cell Physiol
10911370
12 4.08 2000
Lipids: A key role in multidrug resistance? (Review). Int J Oncol
10717249
12 3.079 2000
DNA fragmentation occurs in skeletal muscle during tumor growth: A link with cancer cachexia? Biochem Biophys Res Commun
10753659
20 2.466 2000
The divergent effects of tumour necrosis factor-alpha on skeletal muscle: implications in wasting. Eur Cytokine Netw
11125297
5 2.364 2000
Leptin expression in colorectal and breast cancer patients. Int J Mol Med
10719061
62 2.341 2000
[The role of tumor necrosis factor in the control of fat reserve and obesity]. Med Clin (Barc)
10846690
0 1.125 2000
Does the mechanism responsible for TNF-mediated insulin resistance involve the proteasome? Med Hypotheses
10859639
1 1.066 2000
Calpain-3 gene expression is decreased during experimental cancer cachexia. Biochim Biophys Acta
10806331
10 0 2000
New mediators in cancer cachexia. Nestle Nutr Workshop Ser Clin Perform Programme
11490571
0 0 2000
The role of cytokines in cancer cachexia. Med Res Rev
10232651
50 8.763 1999
Leptin and tumor growth in rats. Int J Cancer
10328224
7 6.513 1999
Mechanism for the increased skeletal muscle protein degradation in the obese Zucker rat. J Nutr Biochem
15539297
8 4.518 1999
Tumour necrosis factor, a key role in obesity? FEBS Lett
10371192
8 3.623 1999
Ubiquitin gene expression is increased in human muscle undergoing neurogenic involvement. Neurochem Int
10213072
2 3.262 1999
Tumour growth and nitrogen metabolism in the host (Review). Int J Oncol
10024680
4 3.079 1999
Resveratrol, a natural product present in wine, decreases tumour growth in a rat tumour model. Biochem Biophys Res Commun
9920811
44 2.466 1999
Leptin administration to lactating rats is unable to induce changes in lipid metabolism in white adipose tissue or mammary gland. Eur J Obstet Gynecol Reprod Biol
10413235
1 1.666 1999
Prevention of cancer and cardiovascular diseases: a common strategy? Med Res Rev
9578984
1 8.763 1998
Protein turnover in skeletal muscle of tumour-bearing transgenic mice overexpressing the soluble TNF receptor-1. Cancer Lett
9751252
29 6.375 1998
Tumour necrosis factor-alpha does not cross the rat placenta. Cancer Lett
9652799
2 6.375 1998
Different cytokines modulate ubiquitin gene expression in rat skeletal muscle. Cancer Lett
9929164
26 6.375 1998
Catabolic proinflammatory cytokines. Curr Opin Clin Nutr Metab Care
10565356
8 4.023 1998
Role of TNF receptor 1 in protein turnover during cancer cachexia using gene knockout mice. Mol Cell Endocrinol
9783914
36 3.754 1998
Short-term effects of leptin on lipid metabolism in the rat. FEBS Lett
9714545
3 3.623 1998
Skeletal muscle UCP2 and UCP3 gene expression in a rat cancer cachexia model. FEBS Lett
9801160
25 3.623 1998
In the rat, tumor necrosis factor alpha administration results in an increase in both UCP2 and UCP3 mRNAs in skeletal muscle: a possible mechanism for cytokine-induced thermogenesis? FEBS Lett
9872400
13 3.623 1998
Tumor growth influences skeletal muscle protein turnover in the pregnant rat. Pediatr Res
9475293
0 2.882 1998
The involvement of the ubiquitin system in Alzheimer's disease (review). Int J Mol Med
9854137
1 2.341 1998
Ubiquitin and proteasome gene expression is increased in skeletal muscle of slim AIDS patients. Int J Mol Med
9854146
22 2.341 1998
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[Treatment of dysphagia of malignant origin with the endoprosthesis of Strecker]. Med Clin (Barc)
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Host metabolism: a target in clinical oncology? Med Hypotheses
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Was tumour necrosis factor-alpha responsible for the fetal malformations associated with thalidomide in the early 1960s? Med Hypotheses
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4 1.066 1998
[Wallstent endoprostheses implanted by fluoroscopic guidance in the palliative treatment of malignant esophageal obstructions and esophago-tracheal fistulas]. Nutr Hosp
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1 0.747 1998
The metabolic basis of cancer cachexia. Med Res Rev
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The ubiquitin system: a role in disease? Med Res Rev
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TNF and pregnancy: the paradigm of a complex interaction. Cytokine Growth Factor Rev
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TNF and AIDS: two sides of the same coin? Med Res Rev
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Lack of effect of eicosapentaenoic acid in preventing cancer cachexia and inhibiting tumor growth. Cancer Lett
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The effects of tumour growth on circulating amino acids in the late pregnant rat. Cancer Lett
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Enhanced leucine oxidation in rats bearing an ascites hepatoma (Yoshida AH-130) and its reversal by clenbuterol. Cancer Lett
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5 6.375 1995
Perturbations of triglycerides but not of cholesterol metabolism are prevented by anti-tumour necrosis factor treatment in rats bearing an ascites hepatoma (Yoshida AH-130). Br J Cancer
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3 6.176 1995
Administration of tumor necrosis factor-alpha results in a decreased placental transfer of amino acids in the rat. Endocrinology
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6 4.286 1995
Marked hyperlipidaemia in rats bearing the Yoshida AH-130 ascites hepatoma. Biochem Soc Trans
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1 2.765 1995
Metabolic effects of tumour necrosis factor-alpha on rat brown adipose tissue. Mol Cell Biochem
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3 2.669 1995
Lipopolysaccharide (LPS) increases the in vivo oxidation of branched-chain amino acids in the rat: a cytokine-mediated effect. Mol Cell Biochem
7476939
1 2.669 1995
Amino acid uptake in skeletal muscle of rats bearing the Yoshida AH-130 ascites hepatoma. Mol Cell Biochem
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1 2.669 1995
Ubiquitin gene expression in skeletal muscle is increased during sepsis: involvement of TNF-alpha but not IL-1. Biochem Biophys Res Commun
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The effects of tumour necrosis factor-alpha on circulating amino acids in the pregnant rat. Cancer Lett
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1 6.375 1994
Interleukin-6 does not activate protein breakdown in rat skeletal muscle. Cancer Lett
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13 6.375 1994
Alanine metabolism in rats bearing the Yoshida AH-130 ascites hepatoma. Cancer Lett
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Anti-tumour necrosis factor-alpha treatment interferes with changes in lipid metabolism in a tumour cachexia model. Clin Sci (Lond)
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Ubiquitin gene expression in skeletal muscle is increased by tumour necrosis factor-alpha. Biochem Biophys Res Commun
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Cytokines and diabetes: the final step? Involvement of TNF-alpha in both type I and II diabetes mellitus. Horm Metab Res
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5 2.268 1994
The effect of chronic tumour necrosis factor-alpha treatment on urinary nitrogen excretion in the rat. Biochem Mol Biol Int
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Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model. J Clin Invest
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76 12.784 1993
Effects of tumor necrosis factor-alpha on muscle-protein turnover in female Wistar rats. J Natl Cancer Inst
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20 12.589 1993
A flow cytometric study of the rat Yoshida AH-130 ascites hepatoma. Cancer Lett
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3 6.375 1993
Tumour necrosis factor-alpha alters the blood compartmentation of amino acids in the rat. Cancer Lett
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Intestinal glucose absorption is lower in obese than in lean Zucker rats. J Nutr
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Intestinal and hepatic nitrogen balance in the rat after the administration of an oral protein load. Br J Nutr
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Tumour necrosis factor-alpha increases the ubiquitinization of rat skeletal muscle proteins. FEBS Lett
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37 3.623 1993
Acute treatment with tumour necrosis factor-alpha induces changes in protein metabolism in rat skeletal muscle. Mol Cell Biochem
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44 2.669 1993
Amino acid metabolism enzyme activities in the obese Zucker rat. Cell Mol Biol (Noisy-le-grand)
8101120
0 0.92 1993
Alanine as a lipogenic precursor in isolated hepatocytes from obese Zucker rats. Cell Mol Biol (Noisy-le-grand)
8220077
2 0.92 1993
The effects of endotoxin administration on blood amino acid concentrations: similarities with sepsis. Cell Mol Biol (Noisy-le-grand)
8374505
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Chronic tumour necrosis factor-alpha treatment modifies protein turnover in rat tissues. Biochem Mol Biol Int
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Effects of tumour necrosis factor-alpha on the enzymatic activities related to glucose metabolism. Biochem Mol Biol Int
8358332
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A simple method for determining the rate of gastrointestinal transit in the rat. Arch Int Physiol Biochim Biophys
7689354
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Interleukin-1 and beta-cell function: more than one second messenger? Endocr Rev
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4 15.745 1992
The role of cytokines in muscle wasting: its relation with cancer cachexia. Med Res Rev
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The enzymatic activities of branched-chain amino acid catabolism in tumour-bearing rats. Cancer Lett
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2 6.375 1992
Effects of tumour necrosis factor-alpha (cachectin) on glucose metabolism in the rat. Intestinal absorption and isolated enterocyte metabolism. Mol Cell Biochem
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3 2.669 1992
Intestinal handling of a glucose gavage by the rat. Mol Cell Biochem
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4 2.669 1992
Amino acid metabolism in several tissues of the obese Zucker rat as indicated by the tissue accumulation of alpha-amino[1-14C]isobutyrate. Mol Cell Biochem
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The DDT method: an alternative to the use of radiolabelled microspheres for the determination of regional blood flows in the rat. Med Hypotheses
1625605
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Rat intestinal amino acid balances after the administration of an oral protein load. Biochem Int
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In the rat, intestinal lymph carries a significant amount of ingested glucose into the bloodstream. Arch Int Physiol Biochim Biophys
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Hepatic accumulation of alpha-aminoisobutyrate in the pregnant rat at term. Biochem Int
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The metabolic fate of an oral 14C-alanine load in the obese Zucker rat. Int J Obes Relat Metab Disord
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The role of insulin in the intestinal absorption of glucose in the rat. Int J Biochem
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Short-term effects of carbon dioxide on carnation callus cell respiration. Plant Physiol
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7 6.456 1991
The energy state of tumor-bearing rats. J Biol Chem
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8 4.125 1991
Lipid metabolism in the obese Zucker rat. Disposal of an oral [14C]triolein load and lipoprotein lipase activity. Biochem J
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Glucose handling by hepatocytes from obese Zucker rats. Biosci Rep
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Effects of starvation on the tissular lipogenic rate in the obese Zucker rat. Biochem Int
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The impairment of respiration by glycolysis in the Lewis lung carcinoma. Cancer Lett
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Rat splanchnic net oxygen consumption, energy implications. J Physiol
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The effects of tumour necrosis factor-alpha (cachectin) and tumour growth on hepatic amino acid utilization in the rat. Biochem J
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The oxidation of leucine in tumour-bearing rats. Biochem J
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[The molecular bases of the cachexia associated with cancer]. Med Clin (Barc)
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Why do cancer cells have such a high glycolytic rate? Med Hypotheses
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Is there a role for lymph in intestinal glucose absorption? Med Hypotheses
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Intestinal amino acid transport: an overview. Int J Biochem
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The obese Zucker rat: a choice for fat metabolism 1968-1988: twenty years of research on the insights of the Zucker mutation. Prog Lipid Res
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Metabolic effects of tumour necrosis factor-alpha (cachectin) and interleukin-1. Clin Sci (Lond)
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Interleukin-1 and lipid metabolism in the rat. Biochem J
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The oxidation of methylglyoxal by mammalian pyruvate dehydrogenase. Arch Biochem Biophys
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Oxidation of branched-chain amino acids in tumor-bearing rats. Biochem Soc Trans
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The respiratory behavior of Lewis carcinoma cells--existence of a cyanide-resistant respiration. Cancer Biochem Biophys
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Amino acid metabolism in tumour-bearing mice. Biochem J
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The metabolic environment of cancer. Mol Cell Biochem
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A nondestructive method for the measurement of radioactive 14CO2 in blood. Anal Biochem
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Effects of a cafeteria diet and starvation of global 14C(U)-glucose disposal. Biochem Int
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A sensitive direct calorimeter for small mammals. J Biochem Biophys Methods
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Blood amino acid compartmentation in mice bearing Lewis lung carcinoma. Cancer Res
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Gas chromatographic method for the estimation of acetone and its metabolites in biological samples. J Chromatogr
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Effects of starvation and a high-energy diet on rat blood compartmentation of injected radioactive alanine and glucose. Biochem Int
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The appearance of 2,3-butanediol in the chronic ethanol treated pregnant rat. Drug Alcohol Depend
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Rat acetoacetate decarboxylase: its role in the disposal of 4C-ketone bodies by the fetus. Horm Metab Res
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On the role of 2,3-butanediol in the metabolism of ethanol. Med Hypotheses
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Simultaneous determination of ketone bodies in biological samples by gas chromatographic headspace analysis. J Chromatogr Sci
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Rat acetoacetic acid decarboxylase inhibition by acetone. Int J Biochem
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Ethanol and acetaldehyde concentrations in the rat foeto-maternal system after an acute ethanol administration given to the mother. Arch Int Physiol Biochim
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Effects of insulin on the disposal of 14C-labelled very low density lipoprotein triglycerides in intact and hepatectomized rats. Diabetologia
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Changes in lipid composition of plasma lipoproteins after total hepatectomy in the rat. Arch Int Physiol Biochim
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Lipids and lipoproteins in maternal and fetus plasma in the rat. Biol Neonate
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LeadR Networks Source: Pubmed Source: ClinicalTrials

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Nb Contacts:
Country Contact count
Spain 74
Italy 34
Netherlands 32
United States 27
Germany 16
Brazil 12
France 6
United Kingdom 5
Chile 4
Sweden 4
Switzerland 4
Canada 3
Argentina 1
Australia 1
Belgium 1
Cyprus 1
Greece 1
Japan 1
New Zealand 1
Portugal 1

LeadR Networks Source: Pubmed Source: ClinicalTrials

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LeadR Networks Source: Pubmed Source: ClinicalTrials

Connection list

Name Organization Country Linked
Busquets Sílvia University of Barcelona Spain 141
Costelli Paola University of Turin Italy 33
Llovera M University of Barcelona Spain 25
Toledo Míriam University of Barcelona Spain 23
Almendro Vanessa Brigham and Women's Hospital United States 22
Ametller Elisabet Institut D'Investigacions Biomediques August Pi I Sunyer Spain 17
Fuster Gemma Institute of Biomedicine of Seville Spain 15
Penna Fabio University of Turin Italy 13
García-Martínez C University of Barcelona Spain 13
Agell Neus University of Barcelona Spain 12
Olivan Mireia University of Barcelona Spain 11
Quinn LeBris S University of Washington United States 10
Barreiro Esther Institut Hospital del Mar d'Investigacions Mèdiques Spain 10
Muscaritoli Maurizio Sapienza University of Rome Italy 9
Alvarez Gonzalez BJ University of Oviedo Spain 8
Alemany Marià University of Barcelona Spain 8
Figueras Maria José Rovira i Virgili University Spain 7
Laviano Alessandro Sapienza University of Rome Italy 7
van Norren Klaske Wageningen University & Research Netherlands 7
Moore-Carrasco Rodrigo University of Talca Chile 7
Serpe Roberto University of Cagliari Italy 7
Fontes-Oliveira Cibely Cristine Lund University Sweden 7
Casado J University of Barcelona Spain 7
Felipe Antonio University of Barcelona Spain 6
Anker Stefan D Charité - University Medicine Berlin Germany 6