|
Embracing cancer complexity: Hallmarks of systemic disease.
|
Cell
38552609
|
0 |
64.5 |
2024 |
|
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
|
Cancer Discov
38581685
|
0 |
28.2 |
2024 |
|
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
|
Nat Cancer
38200244
|
0 |
22.7 |
2024 |
|
Research autopsy programmes in oncology: shared experience from 14 centres across the world.
|
J Pathol
38551513
|
0 |
7.3 |
2024 |
|
Body composition and lung cancer-associated cachexia in TRACERx.
|
Nat Med
37045997
|
2 |
82.9 |
2023 |
|
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
|
Nat Med
37045996
|
7 |
82.9 |
2023 |
|
Lung adenocarcinoma promotion by air pollutants.
|
Nature
37020004
|
28 |
64.8 |
2023 |
|
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
|
Nature
37046094
|
29 |
64.8 |
2023 |
|
The evolution of lung cancer and impact of subclonal selection in TRACERx.
|
Nature
37046096
|
21 |
64.8 |
2023 |
|
Genomic-transcriptomic evolution in lung cancer and metastasis.
|
Nature
37046093
|
9 |
64.8 |
2023 |
|
The evolution of non-small cell lung cancer metastases in TRACERx.
|
Nature
37046095
|
17 |
64.8 |
2023 |
|
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
|
Nature
37055640
|
14 |
64.8 |
2023 |
|
Cachexia: A systemic consequence of progressive, unresolved disease.
|
Cell
37116469
|
4 |
64.5 |
2023 |
|
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
|
Nat Genet
38049664
|
3 |
30.8 |
2023 |
|
Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways.
|
Cancer Discov
36977461
|
4 |
28.2 |
2023 |
|
Insights into the metastatic cascade through research autopsies.
|
Trends Cancer
37059687
|
2 |
18.4 |
2023 |
|
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones.
|
Nat Commun
37563129
|
1 |
16.6 |
2023 |
|
IFN-γ-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis.
|
J Allergy Clin Immunol
37562754
|
0 |
14.2 |
2023 |
|
Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma.
|
Cancer Res
36853169
|
4 |
11.2 |
2023 |
|
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series.
|
J Cachexia Sarcopenia Muscle
37671529
|
3 |
8.9 |
2023 |
|
When can we be confident of surgical cure with ctDNA?
|
Nat Rev Clin Oncol
35798966
|
2 |
78.8 |
2022 |
|
The translational challenges of precision oncology.
|
Cancer Cell
35487215
|
13 |
50.3 |
2022 |
|
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
|
Nat Genet
36253572
|
20 |
30.8 |
2022 |
|
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
|
Nat Cancer
35637401
|
21 |
22.7 |
2022 |
|
Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers.
|
Cell Rep
35830809
|
2 |
8.8 |
2022 |
|
Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF_SELECT consortium assay.
|
NAR Cancer
35664542
|
3 |
0 |
2022 |
|
Using DNA sequencing data to quantify T cell fraction and therapy response.
|
Nature
34497419
|
14 |
69.504 |
2021 |
|
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
|
Cancer Cell
34715028
|
56 |
38.585 |
2021 |
|
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
|
Cancer Discov
33947663
|
37 |
38.272 |
2021 |
|
Tracking Cancer Evolution through the Disease Course.
|
Cancer Discov
33811124
|
38 |
38.272 |
2021 |
|
Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections.
|
BMC Med
33902581
|
61 |
11.15 |
2021 |
|
Large cell neuroendocrine lung carcinoma: consensus statement from The British Thoracic Oncology Group and the Association of Pulmonary Pathologists.
|
Br J Cancer
34489586
|
3 |
9.075 |
2021 |
|
Optimising fusion detection through sequential DNA and RNA molecular profiling of non-small cell lung cancer.
|
Lung Cancer
34536732
|
2 |
6.081 |
2021 |
|
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers.
|
Lancet
32653078
|
104 |
79.321 |
2020 |
|
Scalable and robust SARS-CoV-2 testing in an academic center.
|
Nat Biotechnol
32555528
|
22 |
54.908 |
2020 |
|
Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center.
|
Nat Biotechnol
32681136
|
2 |
54.908 |
2020 |
|
Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
|
Nat Med
32494063
|
1 |
53.44 |
2020 |
|
Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
|
Nat Med
32494064
|
1 |
53.44 |
2020 |
|
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
|
Nat Med
32461698
|
74 |
53.44 |
2020 |
|
Publisher Correction: A clonal expression biomarker associates with lung cancer mortality.
|
Nat Med
32494065
|
0 |
53.44 |
2020 |
|
Pervasive chromosomal instability and karyotype order in tumour evolution.
|
Nature
32879494
|
94 |
49.962 |
2020 |
|
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
|
Nat Genet
32139907
|
71 |
38.33 |
2020 |
|
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
|
Cell Rep
32375028
|
28 |
9.423 |
2020 |
|
Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis.
|
Thorax
33214245
|
17 |
9.102 |
2020 |
|
Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy.
|
Epilepsy Behav
33279440
|
7 |
3.337 |
2020 |
|
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
|
Nat Cancer
32803172
|
35 |
0 |
2020 |
|
Neoantigen-directed immune escape in lung cancer evolution.
|
Nature
30894752
|
316 |
42.779 |
2019 |
|
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
|
Nat Med
31591595
|
74 |
36.13 |
2019 |
|
A clonal expression biomarker associates with lung cancer mortality.
|
Nat Med
31591602
|
34 |
36.13 |
2019 |
|
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
|
Nat Med
31591606
|
64 |
36.13 |
2019 |
|
Inactivation of RB1 and histological transformation in EGFR-mutant lung adenocarcinoma.
|
Ann Oncol
31959334
|
1 |
32.976 |
2019 |
|
Cancer cachexia in thoracic malignancy: a narrative review.
|
Curr Opin Support Palliat Care
31592847
|
3 |
1.618 |
2019 |
|
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.
|
Cell
29656895
|
274 |
36.216 |
2018 |
|
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.
|
Cell
29656894
|
242 |
36.216 |
2018 |
|
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
|
Cancer Cell
29576375
|
263 |
23.916 |
2018 |
|
Genomic instability in mutant p53 cancer cells upon entotic engulfment.
|
Nat Commun
30076358
|
39 |
11.878 |
2018 |
|
Publisher Correction: Genomic instability in mutant p53 cancer cells upon entotic engulfment.
|
Nat Commun
30154405
|
1 |
11.878 |
2018 |
|
KRAS: Reasons for optimism in lung cancer.
|
Eur J Cancer
29894909
|
27 |
6.68 |
2018 |
|
Tracking the Evolution of Non-Small-Cell Lung Cancer.
|
N Engl J Med
28445112
|
893 |
79.258 |
2017 |
|
Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
|
Nature
29258292
|
10 |
43.07 |
2017 |
|
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
|
Nature
28445469
|
624 |
41.577 |
2017 |
|
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
|
Cell
29107330
|
460 |
31.398 |
2017 |
|
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
|
Immunity
28410988
|
174 |
19.734 |
2017 |
|
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.
|
Science
26940869
|
1319 |
37.205 |
2016 |
|
Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer.
|
Ann Oncol
26823523
|
73 |
11.855 |
2016 |
|
Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial.
|
Ann Oncol
26003169
|
42 |
11.855 |
2015 |
|
Translational implications of tumor heterogeneity.
|
Clin Cancer Res
25770293
|
219 |
9.619 |
2015 |
|
The Value of Patient and Public Involvement in Trial Design and Development.
|
Clin Oncol (R Coll Radiol)
26184690
|
5 |
3.236 |
2015 |
|
TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen.
|
BMC Med Genomics
26429708
|
28 |
2.848 |
2015 |
|
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution.
|
Science
25301630
|
522 |
37.205 |
2014 |
|
An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor.
|
Cancer Discov
24520024
|
49 |
20.011 |
2014 |
|
Tracking genomic cancer evolution for precision medicine: the lung TRACERx study.
|
PLoS Biol
25003521
|
82 |
9.797 |
2014 |
|
Implications of intratumour heterogeneity for treatment stratification.
|
J Pathol
24115146
|
23 |
6.894 |
2014 |
|
Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer.
|
Breast Cancer Res Treat
25288231
|
5 |
3.626 |
2014 |
|
Taxane benefit in breast cancer--a role for grade and chromosomal stability.
|
Nat Rev Clin Oncol
23648828
|
22 |
20.693 |
2013 |
|
Tumour heterogeneity and immune-modulation.
|
Curr Opin Pharmacol
23664091
|
12 |
5.363 |
2013 |
|
Bone metastases in germ cell tumours: lessons learnt from a large retrospective study.
|
BJU Int
23795785
|
16 |
4.439 |
2013 |
|
Carboplatin AUC 10 for IGCCCG good prognosis metastatic seminoma.
|
Acta Oncol
22943385
|
5 |
3.156 |
2012 |
|
Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of epidermal growth factor receptor-mutant non-small cell lung cancer metastatic to the brain.
|
Clin Cancer Res
22167408
|
64 |
9.619 |
2011 |
|
Pharmacokinetic evaluation of pixantrone for the treatment of non-Hodgkin's lymphoma.
|
Expert Opin Drug Metab Toxicol
21905966
|
1 |
3.027 |
2011 |
|
Anticancer effects of metformin and its potential use as a therapeutic agent for breast cancer.
|
Future Oncol
21675836
|
15 |
2.131 |
2011 |
|
Laparoscopy: a tool for the diagnosis and treatment of omental torsion.
|
Int J Clin Pract
19143867
|
1 |
2.14 |
2008 |
|
Increased prevalence of ventricular fibrillation in patients with type 2 diabetes mellitus.
|
Heart Vessels
17653519
|
19 |
3.434 |
2007 |
|
Totally extra-peritoneal repair of inguinal hernia by a glove-balloon: technical innovation.
|
Surgeon
17849960
|
1 |
2.558 |
2007 |
